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Was wird bei HbA1c gemessen?
Der HbA1c-Wert gibt an, wie gut die Stoffwechseleinstellung in den letzen 8 bis 12 Wochen war. Hierbei wird ermittelt, wie groß der Anteil des roten Blutfarbstoffes (Hämoglobin) ist, an dem sich der Blutzucker angelagert hat.
Wie aussagekräftig ist der HbA1c?
HbA1c dient zur Diagnostik von Diabetes sowie zur Beurteilung des Therapieverlaufs. Außerdem kann der Wert dazu beitragen, das Risiko für mögliche Langzeitschäden wie etwa Nierenschäden, Erblindung und kardiovaskuläre Erkrankungen abzuschätzen oder gering zu halten.
What is a glycated hemoglobin A1c?
Glycated haemoglobin (hemoglobin A1c, HbA1c, A1C, or Hb1c; is also known as HbA1c or HGBA1c) is a form of hemoglobin which is measured primarily to identify the average plasma glucose concentration over prolonged periods. It is being observed that it is formed in a non-enzymatic glycation pathway by hemoglobin’s exposure to plasma glucose.
What is HbA1c and how is It measured?
Glycated haemoglobin (HbA1c) was initially identified as an “unusual” haemoglobin in patients with diabetes over 40 years ago (12). After that discovery, numerous small studies were conducted correlating it to glucose measurements resulting in the idea that HbA1c could be used as an objective measure of glycaemic control.
Should glucose and HbA1c results be the same in all countries?
Within any country, it is axiomatic that results for glucose and HbA1c should be consistent between laboratories. The National Glycohemoglobin Standardization Program (NGSP) (26) was established following the completion of the Diabetes Complications and Control Trial (DCCT).
What are the disadvantages of home testing for hemoglobin A1c?
Another disadvantage, which applies particularly to home testing of HbA1c by patients, is the fact that the data do not always accurately and completely enter into electronic medical records. Disadvantages aside, there is evidence that point-of-care testing is effective [10,11].